Oh, based off of Casr's responce, I thought peeps were trying it with daggers. 
If you have the AP, It could work. The another disadvantage is the synergy of SnD with potency.
Warning Theory Craft!
Given: 20% chance to do 15 energy is equal to 3 energy per attack on OH average.
Add SnD to a 1.5 speed OH dagger, is an attack per second, or an average 3 energy per second
Hemo save 5 energy every 4 seconds compared to SS.
In theory: potency could provide on average 12 energy per 4 seconds, while hemo only saves 5 per 4 seconds.
Can a mathy type person check that?
I'm curious how serrated blades plays out. + 30%Rupture is clearly great, but I'm curious how effective the armor reduction affects the fight. I would assume as each new encounter come along, mob armor goes higher and higher, allowing serrated blades to always scale with it.
At 60, I raided Hemo with my rouge and often toped meters, but I couldn't do the same in BC. I alway attributed it to combat potency. Energy = extra hits and combo points. It seemed that CP gave more energy than hemo saved. Either way, I am very interested to see how this pans out, got my hemo build cooking...