From a cursory glance at those (I missed the bonus to CoR frm Frailty, good catch!) I'd say it's a toss up with what is better for the raid. Is 3% from Malediction better than 20% to Curse of Recklessness (160 armor reduction). I doubt a raid will want more than one affliction lock. Could a demo spec take frailty so we get both? I'm gonna play with those some and see.
From what I can tell it seems like maybe this is viable for demo spec: http://wotlk.wowhead.com/?talent=I0gZsxczsgoq0stuAoE. I'd bet that Devastation will have to be passed up on demo specs as well as Ruin in favor of Metamorphosis and Frailty. Would be fun to see a warlock with Metamorphisis be raid viable. I'd imagine it's gimmicky and only for fights with lots of adds.
This brings other thoughts to mind, since Improved CoA was brought to tier 1 affliction possibly have the destro lock spec that. I could see the affliction lock doing CoE from Malediction, demo do CoR from frailty, and destro doing CoA from Imp CoA for more dmg pretty easily.